Building a Science Institute for the 21st Century Scripps Research is pioneering a new model for nonprofit research institutes to address the significant health challenges facing humanity in the 21st century, from pandemic threats to the aging of the global population. Founded 100 years ago, Scripps Research is renowned in the life sciences and chemistry for scientific excellence and for training the scientific leaders of tomorrow. Building on this solid foundation, we have established a unique model that seamlessly combines world-class fundamental and translational research to accelerate the development of innovative, new medicines. We believe this model best captures the impact of groundbreaking discoveries for the benefit of human health. Moreover, revenues generated from these new medicines are reinvested into research, creating a self-renewing funding source and business model that amplifies investments in science and their ultimate impact on the public.